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| CBD (cannabidiol) is a non-intoxicating cannabinoid that won’t get you high or affect your mind |
CBD vs THC: What’s the Difference?
Two cannabinoids, very different experiences
CBD and THC are the two most well-known cannabinoids found in cannabis — yet they are often confused or lumped together. While they come from the same plant, their effects on the body and mind are very different.
Understanding the difference helps consumers make informed, responsible choices.
What Is THC?
THC (tetrahydrocannabinol) is the primary psychoactive compound in cannabis. It is responsible for the “high” commonly associated with marijuana.
THC binds strongly to CB1 receptors in the brain, producing effects such as euphoria, altered perception, increased appetite, and impaired coordination.
What Is CBD?
CBD (cannabidiol) is a non-intoxicating cannabinoid. It does not produce a high and does not impair cognitive function.
Instead of binding directly to CB1 receptors, CBD works more subtly by influencing multiple systems in the body, including serotonin and inflammation pathways.
Key Differences at a Glance
- THC: Intoxicating, euphoric, psychoactive
- CBD: Non-intoxicating, calming, supportive
- THC: Can impair coordination and judgment
- CBD: Does not impair mental clarity
How CBD and THC Can Work Together
CBD and THC are not opposites — in fact, they often work best together.
CBD can moderate some of THC’s less desirable effects, such as anxiety or rapid heart rate, while enhancing overall balance through the entourage effect.
Which One Is Right for You?
The answer depends on your goals:
- Choose CBD if you want relaxation, balance, or support without intoxication.
- Choose THC if you’re seeking psychoactive effects or stronger symptom relief.
Many people find the best results come from products that combine both — thoughtfully and in appropriate ratios.
Same plant. Different chemistry. Different experience.
© Tennessee Cannabiz

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